Structure-based network scores for SARS-CoV-2 CD8+ T cell epitopes

Published: 09-06-2021| Version 1 | DOI: 10.17632/3sn3kbn54t.1
Contributor:
Anusha Nathan

Description

Supplemental Figure 3 for article titled "Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses." File includes a list of SARS-CoV-2 epitopes tested by HLA class I-peptide stability assay with highlighted sequences of highly networked, HLA stabilizing epitopes mutated in variants B.1.1.7 (red), B.1.351 (green), P.1 (orange), B.1.617 (purple). Each row indicates a highly networked SARS-CoV-2 epitope and columns include the following: HLA, Peptide #, Epitope Code, Epitope Sequence, Gene, Amino Acid, Protein, Protein Region, Network Score, NetMHC Binding Score, HLA Stabilization Score, 50% Experimental Binder (T/F). Please contact Anusha Nathan at anusha_nathan@hms.harvard.edu with questions.

Files