Patient-reported outcomes associated with different restorative techniques in pediatric dentistry: a systematic review and MTC meta-analysis

Published: 24 November 2018| Version 2 | DOI: 10.17632/47x4scy37y.2
Nathalia Ladewig


Literature searching was carried out on prospective studies indexed in PubMed, Scopus and OpenGrey. A Mixed Treatment Comparisons (MTC) meta-analysis was undertaken considering the results from reviewed studies. Anxiety, pain and quality of life were extracted as mean with standard deviation, presence of pain (%), and mean difference of scores with standard deviation respectively. For direct comparisons, data were combined using a random-effect model. Heterogeneity was assessed with the I2 statistic. For indirect comparisons, the choice between fixed and random effects was made through the comparison of competing models based on the DIC. The expected ranking of efficacy based on the posterior probabilities of all treatment rankings was also calculated.



Universidade de Sao Paulo


Systematic Review with Meta-Analysis