Synergistic effect of capsaicin and docetaxel in prostate cancer cells through AMP-activated kinase
Published: 29 May 2019| Version 1 | DOI: 10.17632/48pfmwbcb5.1
Contributors:
Ines Diaz-Laviada, Belen Sanchez, Alicia Bort, Pedro Mateos, Nieves Rodríguez-HencheDescription
Data used to generate figures of the paper “Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase” Sánchez BG, Bort A, Mateos-Gómez PA, Rodríguez-Henche N, Díaz-Laviada I. Cancer Cell Int. 2019 Mar 8;19:54. doi: 10.1186/s12935-019-0769-2. eCollection 2019. In this study we demonstrate that the spicy ingredient of peepers, capsaicin, sensitizes prostate cancer cell to docetaxel. The metabolic regulator AMPK plays a pivotal role.
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Institutions
Universidad de Alcala de Henares Facultad de Medicina y Ciencias de la Salud
Categories
Prostate Cancer, Docetaxel, Capsaicin, Synergism