Mutations in the lacZ gene

Published: 21 September 2023| Version 1 | DOI: 10.17632/4n3bsmyskj.1
, Matthew Meier,


This is the raw data representing 6,465 independent lacZ mutations from multiple MutaMouse experiments. We curated lacZ mutations from published studies that were collected using a positive selection assay to identify mutations in lacZ that disrupted β-gal function. These 6,465 independent lacZ mutations cause in 2,732 missense mutations that impair β-gal function. The data were used in a publication on the functional mutational landscape of the lacZ gene.


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Genetics, Mutagenicity, Gene Mutation, Mutagenesis, Mutation, Mutation Rate, DNA Mutation, Mutagenesis Study, Mutagen Testing, Computational Biology