Table S1. List of the up-regulated proteins found in the secretome of IL-1β primed MSC.

Published: 16 July 2019| Version 1 | DOI: 10.17632/4r46w7rfsx.1
Brice Magne, Marianne Dedier, Muriel Nivet, Bernard Coulomb, Sebastien Banzet, Jean-Jacques Lataillade, Marina Trouillas


In the present study, we found that, IL-1β-primed gingival MSCs (IL-MSCs) promoted cell migration, dermal-epidermal junction formation and inflammation reduction in vitro, as well as improved epidermal substitute engraftment in vivo. IL-MSCs had different secretory profiles from naive gingival MSCs (NV-MSCs), characterized by an overexpression of TGF-β and MMP pathway agonists. Eventually, MMP-1, MMP-9 and TGF-β1 appeared to be critically involved in IL-MSC mechanisms of action.



Cellular Therapy