Genetic variants of sex hormone levels

Published: 7 May 2024| Version 2 | DOI: 10.17632/4rbzg5mvc3.2
Contributors:
, Huiqing Pan,
,
,
,

Description

The causal relationships between serum sex hormones and COVID-19 susceptibility and severity remain unknown. In this study, we systematically assessed the sex-specific causal effects of serum sex hormone levels, total testosterone (TT), bioavailable testosterone (BT) in particular, on COVID-19 outcomes based on two-sample Mendelian randomization (MR), using summary statistics of genome-wide association studies (GWASs). The data is about number of genetic variants after LD clumping and IVs for each sex hormone levels.

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Institutions

  • Southern University of Science and Technology Department of Biology
  • University of Bristol
  • Tongji University
  • Shanghai Jiao Tong University School of Medicine
  • Shanxi Medical University
  • Shanghai Jiaotong University School of Medicine Xinhua Hospital

Categories

Estradiol, Sex Hormone-Binding Globulin, Testosterone

Funders

  • the Applied Basic Research Project of Shanxi Province, China
    Grant ID: 20210302124186
  • National Natural Science Foundation of China
    China
    Grant ID: 82103949
  • the Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Grant ID: 2021YJRC02

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