Genetic variants of sex hormone levels
Published: 7 May 2024| Version 2 | DOI: 10.17632/4rbzg5mvc3.2
Contributors:
, Huiqing Pan, Shuyan Jin, Dong Liu, , Description
The causal relationships between serum sex hormones and COVID-19 susceptibility and severity remain unknown. In this study, we systematically assessed the sex-specific causal effects of serum sex hormone levels, total testosterone (TT), bioavailable testosterone (BT) in particular, on COVID-19 outcomes based on two-sample Mendelian randomization (MR), using summary statistics of genome-wide association studies (GWASs). The data is about number of genetic variants after LD clumping and IVs for each sex hormone levels.
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Institutions
Southern University of Science and Technology Department of Biology, University of Bristol, Tongji University, Shanghai Jiao Tong University School of Medicine, Shanxi Medical University, Shanghai Jiaotong University School of Medicine Xinhua Hospital
Categories
Estradiol, Sex Hormone-Binding Globulin, Testosterone
Funding
the Applied Basic Research Project of Shanxi Province, China
20210302124186
National Natural Science Foundation of China
82103949
the Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
2021YJRC02