morphology of aortic dissection

Published: 21 April 2021| Version 1 | DOI: 10.17632/4tyj4zxnhm.1
Contributor:
Chang Shu

Description

In this manuscript, the aortic morphology of 112 acute type B aortic dissection (aTBAD) patients and 112 non-aortic disease patients was analyzed via three-dimensional computed tomography imaging. The aortic morphological parameters measured included diameter, length, angulation, tortuosity and aortic arch Myla classification. Risk prediction models were developed to identify the specific geometric risk factors associated with aTBAD. Based on the data, we conclude that incremental aortic arch angulation, tortuosity and type Ⅲ arch configuration could be geometric risk factors that enhance the incidence of aTBAD besides the enlargement of the ascending aorta and aortic arch.

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Aortic diameter and length proximal to the dissection site have been considered the potential risk factors for aTBAD recently. However, this lack of specificity and representativeness limits their clinical application. This manuscript defined aortic morphological parameters, including angulation and tortuosity, and incorporated the Myla classification of the aortic arch into the analysis for the first time. This study aimed to provide the theoretical basis for the assessment of aortic morphology and identify the high-risk patients for aTBAD who may require more aggressive prevention interventions to reduce morbidity and mortality.

Institutions

Central South University

Categories

Natural Sciences

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