[68Ga]Ga-Pentixafor PET/CT images of Glioma patients

Published: 1 March 2023| Version 1 | DOI: 10.17632/4xs94489rw.1
, Habibeh Vosoughi,


This dataset contains information showing chemokine receptor-4 (CXCR4) targeting in high-grade glial brain tumors in treatment-naïve adult patients using a novel radiolabeled PET tracer; [68Ga]Ga-CXCR4 PET/CT. The enrolled patients received the radiotracer intravenously. After approximately 60 minutes, the PET/CT acquisition was performed with a dedicated scanner and in 10 minutes time per bed position. The images were reconstructed and analyzed with the 3D-OSEM algorithm, applying PSF resolution recovery (TrueX in Syngo ® software, Siemens Medical Solution), 3 iterations, and 21 subsets using a 3 mm Gaussian post-smoothing filter. These data would be potentially beneficial for automatic tumor delineation machine learning as well as for differentiation between an active viable tumor vs. post-surgery/necrosis in indeterminate cases. The theranostics potential (CXCR4-tageted labeled beta emitters) is one of the most novel areas of interest for future studies.



Positron Emission Tomography, Glioma, Radiopharmaceutical