Variants in Candidate Genes and their Interactions with Smoking on the Risk of Acute Coronary Syndrome

Published: 14 October 2022| Version 1 | DOI: 10.17632/4zb2r4fxrx.1
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Description

The data correspond to genetic variants related to inflammation, lipid metabolism, and platelet aggregation of subjects from northeast Colombia, and the covariables age, sex, education level, percentage of European ancestry, smoking, diabetes, arterial hypertension, dyslipidemia, and socioeconomic status. We obtained these data to investigate candidate genes' association with Acute Coronary Syndrome (ACS). Furthermore, to evaluate the effects of interactions between polymorphisms and smoking on Acute Coronary Syndrome. The genetic variants are: rs11206510 rs646776 rs599839 rs1800872 rs1800896 rs1799964 rs3798220 rs10455872 rs2227631 rs2230806 rs579459 rs501120 rs1746048 rs964184 rs1861493 rs5918 rs6511720 rs429358 rs7412 rs4420638 The data set is PLINK standard format(1), and it is compounded by the following files: ACS.ped, ACS.map, ACScovariables.txt, Dictionary.txt (Dictionary of variables) 1. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D, Maller J, Sklar P, Bakker PIW de, Daly MJ et al. (2007) PLINK: A tool set for whole-genome association

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Institutions

Universidad Pontificia Bolivariana

Categories

Genetics, Single Nucleotide Polymorphism, Acute Coronary Syndrome

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