Original data of the article entitled “YB-1 recruits Drosha to promote splicing of pri-miR-192 to mediate the proangiogenic effects of H2S.” Zhou Y et al

Published: 15-05-2020| Version 1 | DOI: 10.17632/4zwx862525.1
Contributors:
Yu Zhou,
Xing-Hui Li,
wenlong xue,
Cai-Cai Zhang,
Ming-Jie Wang,
Bo Yu,
Lei Zhu,
Kuhn Leung,
Ying Chen,
Bei-Bei Tao,
Yi-Chun Zhu

Description

miR-192 has a central role for the cells to sense the proangiogenic signals of H2S. The study reveals a new mechanism to regulate microRNA biosynthesis at the primary-to-precursor step in sensing H2S. In addition to H2S donors, the study provides some new potential targets deserves to be explored for anti-ischemia therapies, e.g., approaches based on regulating CSE and miR-192 The file named Zhou Y et al miRNAarray data 20200514 includes the microarray profiling of microRNAs showed a preliminary pattern of changes in the vascular endothelial cells treated with H2S. The file named Zhou Y et al Western Blot data 20200514 includes unedited images for all blots shown in the manuscript.

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