Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 Mutation at single-cell resolution
Published: 19 May 2022| Version 2 | DOI: 10.17632/66fz3h924x.2
Fresh tissue of tubal fimbriated end from 3 BRCA1 carriers (BRCA1_1, 1_2, and 1_3) and 3 non-BRCA1 carriers (Normal_1, _2, and_3) were profiled by 10X genomics single cell RNA sequencing technology. These six samples also profiled by single cell TCR sequencing.
Health Sciences, Ovarian Cancer, BRCA1 Protein