Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 Mutation at single-cell resolution

Name: Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 Mutation at single-cell resolution
Creator: Xuexin Yu
Published: 2022-05-19T18:22:57.595Z
Keywords: Health Sciences, Ovarian Cancer, BRCA1 Protein

Yu, Xuexin

doi:10.17632/66fz3h924x.2

Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 Mutation at single-cell resolution

Published: 19 May 2022| Version 2 | DOI: 10.17632/66fz3h924x.2

Contributor:

Xuexin Yu

Description

Fresh tissue of tubal fimbriated end from 3 BRCA1 carriers (BRCA1_1, 1_2, and 1_3) and 3 non-BRCA1 carriers (Normal_1, _2, and_3) were profiled by 10X genomics single cell RNA sequencing technology. These six samples also profiled by single cell TCR sequencing.

Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 Mutation at single-cell resolution

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