Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain (Vasavda et al., 2022)

Published: 14 June 2022| Version 1 | DOI: 10.17632/67p3n9t437.1
Chirag Vasavda, Risheng Xu, Jason Liew, Ruchita Kothari, Ryan Dhindsa, Evan Semenza, Bindu Paul, Dustin Green, Mark Sabbagh, Joseph Shin, Wuyang Yang, Adele Snowman, Lauren Albacarys, Abhay Moghekar, Carlos A Pardo, Mark Luciano, Judy Huang, Chetan Bettegowda, Shawn Kwatra, Xinzhong Dong, Michael Lim, Solomon Snyder


Table S1. Compound Connectivity Scores for Nfe2l2-derived and Keap1-derived transcriptome signatures. Table S2. Differential gene expression in primary human dermal fibroblasts treated with vehicle or JQ-1. Table S3. Gene ontology analysis of JQ-1-dependent differential gene expression.



Johns Hopkins Medicine


Neuroscience, Pharmacology, RNA Sequencing, Trigeminal Neuralgia