Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain (Vasavda et al., 2022)

Published: 14 June 2022| Version 1 | DOI: 10.17632/67p3n9t437.1
Chirag Vasavda,
Risheng Xu,
Jason Liew,
Ruchita Kothari,
Ryan Dhindsa,
Evan Semenza,
Bindu Paul,
Dustin Green,
Mark Sabbagh,
Joseph Shin,
Wuyang Yang,
Adele Snowman,
Lauren Albacarys,
Abhay Moghekar,
Carlos A Pardo,
Mark Luciano,
Judy Huang,
Chetan Bettegowda,
Shawn Kwatra,
Xinzhong Dong,
Michael Lim,
Solomon Snyder


Table S1. Compound Connectivity Scores for Nfe2l2-derived and Keap1-derived transcriptome signatures. Table S2. Differential gene expression in primary human dermal fibroblasts treated with vehicle or JQ-1. Table S3. Gene ontology analysis of JQ-1-dependent differential gene expression.



Johns Hopkins Medicine


Neuroscience, Pharmacology, RNA Sequencing, Trigeminal Neuralgia