Non-Hemolytic Antimicrobial Peptides Predicted from Omics Data of Cephalopods' Posterior Salivary Glands

Published: 7 September 2023| Version 1 | DOI: 10.17632/6gsdfj9876.1
Guillermin Agüero-Chapin, Dany Domínguez-Pérez, Yovani Marrero-Ponce


This dataset compiles non-hemolytic antimicrobial peptides (AMPs) consistently identified within omics data extracted from Cephalopods' Posterior Salivary Glands (PSG). It gathers non-redundant and non-hemolytic AMPs that were predicted across the 13 non-hemolytic AMP datasets reported in (doi: 10.17632/tr7xbp2pyt.1). These latter datasets stemmed from agreed non-hemolytic predictions by three models on AMPs libraries resulting from screening enzymatically-digested proteins extracted from Cephalopods' PSG (doi: 10.17632/6fjsdnvygb.1). This dataset represents a potential source of privileged AMPs for further exploration and drug development.


Steps to reproduce

The creation of this dataset involved two key steps: 1. The initial peptide libraries, accessible via doi: 10.17632/tr7xbp2pyt.1, were combined. 2. To eliminate sequence redundancy, CD-HIT was utilized with a sequence identity threshold set at 0.98


Universidade do Porto Centro Interdisciplinar de Investigacao Marinha e Ambiental


Biodiscovery, Cephalopoda, Omics, Peptide Library, Antimicrobial