Endothelial cells under therapy-induced senescence secrete CXCL11, which increases aggressiveness of breast cancer cells

Published: 22 October 2019| Version 2 | DOI: 10.17632/6mdt6t67pn.2
Hyun Jung Hwang


Together, our results demonstrated that SASP from endothelial cells experiencing therapy-induced senescence promotes the aggressive behavior of cancer cells, and that CXCL11 could potentially be targeted to prevent the adverse effects of therapy-induced senescent endothelial cells on the tumor microenvironment