Prior infection with an unrelated neurotropic virus exacerbates influenza disease, impairs lung CD8+ T cell responses and promotes generation of brain tissue-resident memory pools

Name: Prior infection with an unrelated neurotropic virus exacerbates influenza disease, impairs lung CD8+ T cell responses and promotes generation of brain tissue-resident memory pools
Creator: Isabelle Foo
Published: 2023-08-09T11:55:24.508Z
Keywords: Immunology, Virology, Influenza, Mouse Study, Arbovirus, Co-Infection

Foo, Isabelle; Chua, Brendon; Clemens, E. Bridie; Chang, So Young; Jia, Xiaoxiao; McQuilten, Hayley; Yap, Ashley; Cabug, Aira; Ashayeripanah, Mitra; McWilliam, Hamish; Villadangos, Jose; Evrard, Maximilien; Mackay, Laura; Wakim, Linda; Fazakerley, John; Kedzierska, Katherine; Kedzierski, Lukasz

doi:10.17632/6xb4j8xtv5.1

Prior infection with an unrelated neurotropic virus exacerbates influenza disease, impairs lung CD8+ T cell responses and promotes generation of brain tissue-resident memory pools

Published: 9 August 2023| Version 1 | DOI: 10.17632/6xb4j8xtv5.1

Contributors:

, Brendon Chua, E. Bridie Clemens, So Young Chang, Xiaoxiao Jia, Hayley McQuilten, Ashley Yap, Aira Cabug, Mitra Ashayeripanah, Hamish McWilliam, Jose Villadangos, Maximilien Evrard, Laura Mackay, Linda Wakim, John Fazakerley, Katherine Kedzierska, Lukasz Kedzierski

Description

Number and frequency of CDR3ab clonotypes within DbNP366+CD8+ and DbPA224+CD8+ T cells detected in the lung and brain of IAV and SFV→IAV infected mice.

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The University of Melbourne

Prior infection with an unrelated neurotropic virus exacerbates influenza disease, impairs lung CD8+ T cell responses and promotes generation of brain tissue-resident memory pools

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