TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells enforced by BLIMP1 (Main Figures)

Published: 25 September 2025| Version 1 | DOI: 10.17632/6xjrfdh9pz.1
Contributor:
Maegan Murphy

Description

These data correspond to the main figures of the manuscript titled, "TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells enforced by BLIMP1." Within the Figure_1.zip file, files include raw qPCR data with calculated delta Ct values, raw MFI values for in vitro stimulated WT and KO CD8+ T cells corresponding to Figure 1E and F, and fcs files of flow data presented in figures 1 E and F. Within the Figure_2.zip file, files include the raw fcs files corresponding to panels A, C, and D. Sample information pertaining to each panel is provided in an excel file enumerating the cell culture conditions and genotypes of each sample. An excel file containing the raw numerical data of percent TCF1 positive for each sample in panel 2B is also provided. Within the Figure_3.zip file, files include the raw fcs files corresponding to the representative plots in panels B, C, E, H, and J. Excel files containing the raw numerical data for graphs in panels B, C, D, F, G, H, and K are also included. Within the Figure_4.zip file, files include the raw fcs files corresponding to the representative plots in panel G. An Excel file containing the raw numerical data for graphs in panel G. The genomic data have been separately uploaded to the NCBI GEO database. Within the Figure_5.zip file, files include the raw fcs files corresponding to the representative plots in panels A, B, E, and G. Excel files containing the raw numerical data for graphs in panels A, B, C, E, F, G, H, and I are also included. Within the Figure_6.zip file, files include the raw fcs files corresponding to the representative plots in panels A, B, and E. Excel files containing the raw numerical data for graphs in panels A, B, C, F, and H. Within the Figure_7.zip file, files include the raw fcs files corresponding to the representative plots in panel A. Excel files containing the raw numerical data for graphs in panels B, F, and H are also included. The genomic data have been separately uploaded to the NCBI GEO database.

Files

Institutions

Washington University in St. Louis

Categories

Immunology

Licence