HINT1 gene polymorphisms rs3864236, rs2526303, rs2551038, and personality traits measured by NEO-FFI and STAI in a group of cigarette users and never-smokers.

Published: 19 December 2024| Version 2 | DOI: 10.17632/72h228rp33.2
Contributors:
, AGNIESZKA BORON, Krzysztof Chmielowiec, Aleksandra Strońska-Pluta, Jolanta Masiak, Milena Lachowicz, Jolana Chmielowiec, Joanna Janiszewska-Olszowska, Grzegorz Trybek, Anna Grzywacz

Description

The dataset includes 522 participants (371 cigarette users and 151 never-smokers) with their age, sex and smoking status. Both cigarette users and controls were examined using the NEO Five-Factor Personality Inventory (NEO-FFI) and the State-Trait Anxiety Inventory (STAI). NEO-FFI analyses five traits - neuroticism, extroversion, openness to experience, agreeableness, and conscientiousness. STAI measures anxiety as a trait and as a state. The results of NEO-FFI and STAI were expressed as sten scores. The conversion of the raw score to the sten scale was conducted by the Polish standards for adults, with a sten value of 0-3 corresponding to low results, 4–6 corresponding to average results and 7–10 corresponding to high results. The histidine triad nucleotide-binding protein (HINT1) gene's three polymorphic sites were genotyped: rs3864236, rs2526303, and rs2551038.

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Institutions

Pomorski Uniwersytet Medyczny w Szczecinie

Categories

Psychology, Public Health, Neurochemistry, Behavior Genetics

Funding

National Science Center

2021/05/X/NZ7/01089

Licence