Viral fitness landscapes in diverse host species reveal multiple evolutionary lines for the NS1 gene of influenza A viruses - Supplemental Data (Part 1)

Published: 22-10-2019| Version 1 | DOI: 10.17632/77x6pyfk79.1
Raquel Munoz-Moreno,
Carles Martinez-Romero,
Daniel Blanco-Melo,
Christian V. Forst,
Raffael Nachbagauer,
Asiel Benitez,
Nacho Mena,
Sadaf Aslam,
Vinod Balasubramaniam,
Maryline Panis,
Juan Ayllon,
David Sachs,
Man-Seong Park,
Florian Krammer,
Benjamin R. tenOever,
Adolfo Garcia-Sastre


We designed a barcoded viral library of recombinant influenza A viruses expressing a selection of NS1 from different strains, hosts, countries and years. Each virus was individually rescued and deep-sequenced using the Illumina MiSeq platform to verify viral genome integrity and sequence. This dataset includes Illumina deep-sequencing raw data of each virus included in the final library (barcodes 1-123).