Differential association analysis between two COVID-19 hospitalization GWAS from HGI

Description

COVID-19 hospitalization GWASs, including HGI-B1 (hospitalized vs. non-hospitalized) and HGI-B2 (hospitalized vs. general population) are compared for effect sizes of each SNP using Z-test with/without normalization. The two GWASs were downloaded from HGI (release 4), and samples used to generate the two GWASs were with mixed ancestries. Only SNPs with MAF>0.01 and imputation score > 0.6 were kept. The aim for the comparison is to identify potential COVID-19 risk SNPs showing ancestry-linked effects. Please read detail of the analysis by accessing the SAS GWAS Analyzer in GitHub (https://github.com/chengzhongshan/COVID19_GWAS_Analyzer).

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