Effects of fucoidan on the HCoV-OC43 induced expression of chemokines, cytokines and viral responsive genes in MRC-5 cells

Published: 23 March 2023| Version 1 | DOI: 10.17632/7fxrsc8fmn.1


To illustrate more comprehensively the effect of fucoidan on HCoV-OC43 infected cells, we profiled the gene expression of HCoV-OC43 infected MRC-5 cells treated and un-treated with fucoidan (U. pinnatifida) over a period of six hours by using RNA sequencing to dissect viral activity and chemokine/cytokine responsive genes. Dataset included Differential Expression Gene (DEG) Analysis and GO classification of up-regulated and down-regulated genes of viral activity and chemokines/cytokines. GO classification of DEGs, which reflects in the biological process, cellular component, and molecular function.



National Health Research Institutes Institute of Biotechnology and Pharmaceutical Research


Biochemical Pharmacology, RNA Sequencing, Natural Compound