Acute kidney injury complicating critical forms of COVID-19: risk factors and prognostic impact

Published: 28 February 2024| Version 2 | DOI: 10.17632/7m4g8w3hzs.2
Contributors:
jihene guissouma, Hana Ben Ali, Hend Allouche, Insaf Trabelsi, Olfa Hammami, Yosra Yahia, Hatem Ghadhoune

Description

This was a retrospective descriptive case/control monocentric study carried out in the medical ICU of Bizerte hospital (a tertiary teaching hospital in north of Tunisia) over a period of 18 months (September 2020-February 2022). This medical ICU is managed by medical intensivists with a novel unit of six beds created for the COVID-19 outbreak. In this study we aimed to assess the incidence, the risk factors and the prognostic impact of AKI complicating critical forms of COVID-19.

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a retrospective descriptive case/control monocentric study carried out in the medical ICU of Bizerte hospital (a tertiary teaching hospital in north of Tunisia) over a period of 18 months (September 2020-February 2022). All adult patients (>18 years) admitted to the ICU for critical forms of COVID-19 during the study period were included. Patients with a history of chronic renal failure and those who did not meet the critical COVID-19 criteria were excluded. Patients were divided in two groups: the case group which included the critical COVID-19 patients who developed AKI during their ICU stay: AKI patients, and the control group which included those who maintained normal renal function: No AKI patients. We focused for each patient on demographic and clinical features, initial laboratory findings, initial thoracic computed tomography (CT) scan data, drugs received prior to AKI onset, respiratory support, renal function during hospitalization, need for RRT, ICU length of stay (LOS) and mortality. Data were analysed with Jamovi free software, The risk factors for AKI and those associated with ICU mortality were screened with the univariate logistic regression model.

Institutions

Universite de Tunis El Manar Faculte de Medecine de Tunis

Categories

Acute Renal Failure, COVID-19

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