Cognitive evaluation, baseline-EEG, and EEG features extraction in people living with HIV

Description

The ethics committee of the Autonomous University of Baja California (UABC) approved the protocol for the acquisition of electroencephalogram records. All cases used the 10-20 system to place the electrodes and 19 electrodes were used with a recording time of 16 to 21 minutes. A monopolar assembly referenced to the short-circuited earlobes, using a Medicid 4 system (Neuronic Mexicana). During the EEG recording, the participants remained comfortably seated in a room with no light. The sampling frequency was 240Hz, with a resolution of 16 bits, a low-pass filter of 0.5 Hz, and a high-pass filter of 30 Hz, as well as a Notch filter of 50/60 Hz. The cases belong to adults with HIV, with a history of drug use (polydrug use, amphetamines), multiple vulnerability factors (deported migrants, homosexuality, and in some cases a history of having been in prison). The qEEG in HIV reports excess delta activity and low alpha activity. HIV-associated neurocognitive impairment or disorder can occur from an early age with impairments in memory, learning, and executive functions. In addition to age, schooling, gender, and group, the global average cognitive score obtained in the cognitive tests is also recorded, as well as the average obtained by the cognitive domain. The global average cognitive score was obtained with the cognitive tests Stroop test, Verbal Fluency test, Hopkins Learning Verbal test- Revised, and Wisconsin Sorting Card test. In the database, there are also data on years of evolution of HIV, functionality as scores of the Karnofsky scale, and whether there is or there isn’t impairment in the cognitive domains of information processing speed, verbal fluency, memory, and executive functioning.

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