Data for: Simvastatin Inhibits the Proliferation of HL-60 Clone 15- Derived Eosinophils by Inducing the Arrest of the Cell Cycle in the G1/S Phase

Published: 23 May 2019| Version 1 | DOI: 10.17632/83hs9ks6j7.1
Jong-Hwei Pang


This database is the original data demonstrating the decrease of ECP expression of eosinophils in the cell model and an allergic animal model after simvastatin treatment was not due to inhibition of ECP formation or its release but the decrease of cell counts. Simvastatin induced G1/S cell cycle arrest and the associated cyclin A to inhibit subsequent HC15 cell proliferation via the mevalonate pathway.



Statin, Database