Dataset for the evaluation of tongue alterations in ALS by sonographic and 3T-MRI imaging
This dataset contains cross-sectional and longitudinal tongue images and assessments obtained from 206 ALS patients and 104 age- and sex-matched controls that underwent high-resolution ultrasound (HRUS) and 3T MRI. In each image, the tongue is delineated in an additional region of interest (ROI) file provided for each of the coronal cross-sections acquired via HRUS and the midsagittal slices from the sagittal cerebral 3D-MPRAGE 3T MRI of the head. For these ROIs size and mean intensity markers are calculated. From the MRI images quantitative parameters for the shape and relative position of the tongue are derived. For each individual in the dataset these obtained markers are provided along with demographic and disease specific information in accompanying lists. The dataset can be combined with other data to increase statistical power or to extend the analysis with more advanced algorithms to implement and study additional markers for size, shape or texture of the tongue in ALS patients and controls.