Stress Paradigms, Attentional Bias, and Craving for Cigarettes and Opioids

Published: 9 May 2024| Version 1 | DOI: 10.17632/8xhtkkx3dz.1
Gopalkumar Rakesh


This spreadsheet encompasses data for a lab based experiment. We simultaneously administered two validated stress paradigms to model physical (cold pressor test [CPT]) and psychological stress (paced auditory serial addition task [PASAT]) in people with OUD who smoke (n=14), stabilized on medications for OUD. We examined the effects of stress on cigarette and opioid craving and attentional bias (AB) for both cigarette cues and opioid cues using an eye tracker. The data presented in this manuscript was acquired as part of a randomized controlled trial (RCT) comparing the effects of four sessions of active versus sham intermittent theta burst stimulation (iTBS) versus sham iTBS on craving and cue-based AB for cigarettes and opioids (NCT05049460). All data in the present study were from baseline assessments collected before iTBS/sham iTBS. The study was approved by the Institutional Review Board at the University of Kentucky College of Medicine. Column 1 is the unique participant identification number, column 2 lists time points ( 0 being baseline and 1 being after stress), column 3 listing cue types (1 being cues of people smoking cigarettes or using opioids, 2 being cues of cigarette paraphernalia or opioid paraphernialia), column 4 lists Fagerstrom scores of participants, column 5 lists cigarette craving scores (Short version of Tobacco Craving Questionnaire, TCQ-SF), column 6 lists cue based AB for cigarette cues in milliseconds, column 7 lists opioid craving scores (opioid craving scale, OCS), column 8 lists cue based AB for opioid cues.



University of Kentucky College of Medicine


Tobacco, Craving for Drug, Attentional Bias, Opioid Abuse, Physical Stress