BAP1 in lung adenocarcinoma and thyroid

Published: 26 June 2018| Version 1 | DOI: 10.17632/93tzdsyc4c.1
Rola M Farid,
- Rasha M. Abd El Atti,
Nermine M. Abd Raboh


BAP1 mutations influence the development of multiple tumors and are associated with poor prognosis. Its germline mutations are associated with hereditary cancer known as BAP1-tumor predisposing syndrome. Somatic mutations of BAP1 were identified after recognition of germline mutations in corresponding sporadic tumors.