Antibiotic resistance and changes in microbial arsenic processes through genetic and functional connections in groundwater
Description
This repository contains the numerical source data and process-model code associated with the manuscript entitled “Antibiotic resistance and changes in microbial arsenic processes through genetic and functional connections in groundwater”. The deposited data include the values underlying the main-text and Supplementary figures and tables. The repository includes: (i) groundwater hydrochemical variables, aqueous As(III) and As(V) concentrations, and antibiotic concentrations; (ii) processed microbial taxonomic profiles and abundances of arsenic-related genes, antibiotic resistance genes and mobile genetic elements used in the reported figures and analyses; (iii) contig-level records of arsenic-related and antibiotic resistance gene co-localisation; (iv) transcript and protein abundance data for arsenic transformation, antibiotic resistance and associated stress-response functions; and (v) measured aqueous arsenic speciation, model inputs, reconstructed endpoints and sensitivity-analysis results. The repository also contains the Python script, fixed parameter settings and software requirements for the exploratory process model of aqueous arsenic speciation. These materials support reproduction of the model’s internal calibration, comparisons among the five predefined configurations and one-at-a-time sensitivity analysis. Raw sequencing reads and mass-spectrometry files are not included in this repository.