Data for: Dynamical phase transition in spike neuronal firing patterns of hippocampal cells
Description of this data
To determine the dynamical state of the neurons, we have focused on the statistics of the distributions of inter-spike intervals. In particular, we identify two states. The first is the basal state, in which cell spiking follows non-correlated (memory-less) random statistics, usually with a Poisson-like distribution of intervals. The second state is obtained by the activation of the phospholipase C (PLC) signaling cascade with oxotremorine-M (Oxo-M), a M1 receptor agonist, which introduces temporal correlations in the spiking intervals. We interpret these correlations as a shift of the neuronal dynamics towards a critical state. We corroborate that this shift in dynamics is due to a change in the M-channel by applying the specific channel blocker XE991, as well as by blocking the phospholipase C (PLC) with U73122.
Experiment data files
This data is associated with the following publication:
Cite this dataset
Rivera, Ana Leonor; Bravo-Martinez, Jorge (2019), “Data for: Dynamical phase transition in spike neuronal firing patterns of hippocampal cells”, Mendeley Data, v1 http://dx.doi.org/10.17632/9d6jhgnr2x.1