Cancer hallmarks

Published: 16 July 2021| Version 1 | DOI: 10.17632/9mrc3b54g2.1
Arlen James Mosquera Ruiz


In these files there are data that represent expression profiles of candidate genes that resulted from applying two methodologies using the genes linked to the Cancer Hallmarks. There is also a file that summarizes a systematic literature search that was carried out with a group of candidate genes to find out if they were related to carcinogenesis processes in vivo or in vitro.


Steps to reproduce

The information on the expression profiles was extracted using the GEPIA2 database. The values are expressed in transcripts per million. To extract the information, each candidate gene was simply entered and the mean expression values were directly extracted from the interactive bar graphs offered by the platform. Subsequent analyzes (grouping genes by tissue, for example) were done using the multi-list comparison tool offered by the website called molbiotools. On the other hand, the systematic literature review was carried out using the Pubmed database. The articles that were in a time range from 2019 to 2021 were preferably chosen. Keywords were used that related the genes to the carcinogenesis process in vivo or in vitro.


Pontificia Universidad Javeriana - Cali


Bioinformatics, Systems Biology, Cancer, Gene Expression