Vitamin D supplementation and cardiac function.

Published: 11 September 2019| Version 1 | DOI: 10.17632/b98drwjsr2.1
Matteo Briguglio


Raw data of the clinical trial NCT03403933. We enrolled 47 older adults scheduled for major orthopaedic surgery and suffering from hypovitaminosis D. Patients underwent 6-months calcifediol supplementation with a starting dose at first post-operative day of 50 µg/die in liquid preparation. Down-titration to 20 µg/die at 3-months assessment was planned. Cardiac performance was evaluated by measuring left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) during pre-operative assessments and at 1-month, 3-months, 6-months follow-ups. The dataset was used to write the article "Correction of hypovitaminosis D improved global longitudinal strain earlier than left ventricular ejection fraction in cardiovascular older adults after orthopaedic surgery", which was published by the Journal of Geriatric Cardiology in 2018.