Epigenetic reprogramming of CAMSC

Published: 21-10-2020| Version 1 | DOI: 10.17632/bdywxt6cvv.1
Contributor:
Lan Coffman

Description

Ovarian cancer epigenetically reprogram normal mesenchymal stem cells into carcinoma-associated mesenchymal stem cells (CA-MSCs). This reprogramming is characterized by enhancer-enriched DNA hypermethylation, altered chromatin accessibility and differential histone modifications.

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