Supplemental material for JAAD publication titled - A Retrospective study of Nail Squamous Cell Carcinoma at a Single Tertiary Center: A Relationship between longitudinal melanonychia and depth of invasion
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Supplemental materials for, Title: A Retrospective study of Nail Squamous Cell Carcinoma at a Single Tertiary Center: A Relationship between longitudinal melanonychia and depth of invasion Authors: Jongeun Lee, M.D., Dong Min Shin, M.D., Se Jin Oh, M.D., Ji-Hye Park, M.D., Ph.D., Dongyoun Lee, M.D.,Ph.D. Supplementary figure 1. Clinical presentations of the 20 cases of NSCC. Supplementary figure 2. Dermoscopic images of NSCC with melanonychia (case 1, 2, 3, and 4). The dotted line represents parallel line from the widest part of the melanonychia. Supplementary figure 3. Clinical images of case 10. (A) The patient complained of a non-healing ulcerative lesion on the fourth finger of the left hand that started five years earlier. (B,C) Seven months later, a hyperkeratotic lesion developed below the nail plate. Supplementary figure 4. Histopathologic features of NSCC in-situ with longitudinal melanonychia and invasive SCC. (A) Histopathology of case 3 revealed melanin granules with atypical squamous cells (hematoxylin & eosin [H&E], ×40; Inset: ×400). (B) Histopathology of case 17 showed marked acanthosis with atypical cells, and dermal invasion was present (H&E, ×40; Inset: ×400).