Quality of life assessment following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for appendiceal neoplasms and malignancies: electronic patient related outcome measurements (ePROMs)
Description
Patient data extracted from The Christie Foundation Trust's EPR system for the paper entitled "Quality of life assessment following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for appendiceal neoplasms and malignancies: electronic patient related outcome measurements (ePROMs) ". Data includes patient demographics (age, sex, BMI, ECOG PS, smoking status), disease factors (pathology, PCI, CC score) and QoL outcomes (EQ-5D). This dataset includes 200 entries/participants and approx 130 variables.,
Files
Steps to reproduce
Patient demographics were summarised using the median and interquartile range (IQR) for continuous data and proportions for categorical data. The proportion of patients reporting each level of each EQ-5D domain was compared over the 2 time points and the Chi-squared test was used to compare differences between time points. The median EQ-VAS score was compared over the 2 time points and the Mann-Whitney U test used to compare differences between time points. Multivariable logistic regression models were fitted to evaluate the association between EQ-5D scores ≥ 2 and patient and cancer factors, adjusting for age, BMI, ECOG performance status, positive smoking history and PCI score. For logistic regression models, ePROMs entries regardless of the time elapsed post-surgery were included. P-values of ≤ 0.05 were considered statistically significant.