A microbial derived bile acid acts as GPBAR1 agonist and RORγt inverse agonist and reverses inflammation in inflammatory bowel disease

Published: 15 March 2024| Version 1 | DOI: 10.17632/cdffdhvxnc.1
Contributors:
Michele Biagioli, silvia marchianò,

Description

The interplay between the gut microbiota, bile acids and the immune is a critical determinant in development of inflammatory bowel disease (IBD). Here investigated the fecal bile acid profiles, gut microbiota composition, and immune responses in IBD patients and murine models of colitis.

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Institutions

Universita degli Studi di Perugia

Categories

Transcriptome, Metagenomic Next-Generation Sequencing

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