Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager

Published: 13 June 2023| Version 1 | DOI: 10.17632/crk9tmnmb7.1
Contributors:
Samira Anbari, Hanwen Wang, Yu Zhang, Jun Wang, Minu Pilvankar, Masoud Nickaeen, Steven Hansel, Aleksander S. Popel

Description

This repository contains the QSP platform for combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager developed by the Popel Systems Biology Laboratory. https://popellab.johnshopkins.edu/.

Files

Steps to reproduce

Refer to the readme file

Institutions

Johns Hopkins University

Categories

Mathematical Modeling, Pharmacodynamics, Pharmacokinetics, Cancer Immunotherapy

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