Sphingosine 1-phosphate receptor 2 is central to maintaining epidermal barrier homeostasis

Published: 02-04-2020| Version 1 | DOI: 10.17632/csrs6vw8ps.1
Contributors:
Satomi Igawa,
Ayaka Ohzono,
Phoebe Pham,
Zhenping Wang,
Anna Di Nardo,
Teruaki Nakatsuji,
Tatsuya Dokoshi

Description

We showed that S1P and its receptor S1PR2 are involved in maintaining the epidermal barrier homeostasis by controlling tight junction related proteins, corneodesmosin, and filaggrin2 expression.

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