Esketamine vs Control in Bariatric Surgery Patients

Published: 20 February 2023| Version 1 | DOI: 10.17632/cxtkvr786g.1


Methods: We enrolled 68 patients between the ages of 18 and 50 who were planned to have bariatric surgery and had a Body Mass Index of less than 27 kg/m2 and an American Society of Anesthesiologists Physical Status of I to III. They were split into the Control Group and the Esketamine Group. During the procedure, the latter group also received various anesthetic medications along with a loading dosage of esketamine of 0.2 mg/kg and a maintenance dose of 0.2 mg/(kg.h). The former group was given a placebo. While other surgical data was being recorded throughout the surgery, they were evaluated for NRS pain scores and PONV scores afterward. Results: The 0.5h, 1h, 2h, 6h, and 12h NRS scores in the esketamine group were significantly lower than those in the control group. There was also a significant overall decrease in the highest and lowest NRS scores (p0.05), as well as a decrease in the number of extra painkillers given to the esketamine group. However, the opioid medication utilized post-operatively did not differ significantly from the control group (p>0.05).


Steps to reproduce

Data were collected on paper and then recorded into an excel file, and then copied to SPSS 26 after variables were created. Mean Arterial Pressure and Adjusted body weight were calculated using excel formulas.


Anesthesia, Bariatric Surgery


Sichuan Informatics Association of Tradition Chinese Medicine