Silybin restores glucose uptake after tumor necrosis factor alpha and lipopolysaccharide stimulation in 3T3-L1 adipocytes

Published: 13 April 2023| Version 1 | DOI: 10.17632/df7d6h8kmc.1
Contributor:
Anahi Chavarria

Description

This data accompanies the paper Butanda et al (2023) "Silybin restores glucose uptake after tumor necrosis factor alpha and lipopolysaccharide stimulation in 3T3-L1 adipocytes".

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Steps to reproduce

3T3-L1 adipocytes were pre-incubated with silybin for 24 h and then challenged with TNFα or lipopolysaccharide (LPS), or adipocytes were first challenged with the inflammatory stimuli and then post-treated with silybin. After, TNFα levels, glucose uptake, and membrane GLUT4 expression were determined.

Categories

Glucose, Tumor Necrosis Factor, Adipocyte, Flavonoid

Funders

  • Instituto Politécnico Nacional
    Grant ID: SIP20180722
  • Universidad Nacional Autónoma de México
    Grant ID: PAPIIT IN214821
  • Consejo Nacional de Ciencia y Tecnología (CONACYT)
    Grant ID: Ciencia de Frontera 2019-1783
  • Consejo Nacional de Ciencia y Tecnología (CONACYT)
    Grant ID: FORDECYT-PRONACES/263957

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