Data for: Synthesis of 2-oxo-acetamidines via copper-catalyzed oxidative cross-coupling of α-amino ketone compounds with amines

Published: 29-08-2019| Version 1 | DOI: 10.17632/dng6ybk9xr.1
Contributor:
Wei Deng

Description

A general and efficient method for the synthesis of 2-oxo-acetamidines via copper-catalyzed oxidative cross-coupling of amines with α-amino ketone compounds was achieved. In this reaction, the C−N bond of α-amino ketone is broken and new C−N and C=N bonds are constructed in one single transformation. This reaction system has a broad substrate scope and provides a facile pathway for the synthesis of 2-oxo-acetamidines.

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