miR-371b-5p and miR-155-5p

Published: 28 May 2017| Version 1 | DOI: 10.17632/f3w23wkxw7.1
Yang Liu


These findings in accordance with our results that miRNAs involved in the pathogenesis of metabolic disorders in EAT of CAD patients. Overall, we were able to depict a novel miRNA signature of EAT in CAD patients characterized by a disregulated of miRNAs profile that are probably involved in pathogenesis of CAD. The results were validated by qRT-PCR and cell transfection. The results of the current study support the hypothesis that miRNA expression is deregulated in epicardial adipose tissue in patients suffering from CAD disease. We provided a comprehensive potential novel miRNAs expression signature of EAT in CAD patients, and we showed that the targets of the miRNAs are necessarily associated to the pathogenesis of CAD.



Bioinformatics, Microarray, RNA Gene