Data for: Inhibitory and facilitatory connections from dorsolateral prefrontal to primary motor cortex in healthy humans at rest - An rTMS study

Published: 27 September 2018| Version 1 | DOI: 10.17632/f69vzth9dj.1
Xiaoying Tan


Here we introduce theta burst stimulation (TBS)-based protocols to target the inhibitory and facilitatory connections in DLPFC-M1 network. Intermittent and continuous theta burst stimulation with 600 pulses (iTBS600/cTBS600) were applied to left DLPFC and resting motor threshold (RMT), motor evoked potential (MEP) and short-interval intracortical inhibition (SICI) were measured with transcranial magnetic stimulation to the ipsilateral primary motor cortex. We found that iTBS600 on the DLPFC decreased the MEP amplitude of the M1. Conversely, cTBS600 on the DLPFC increased the MEP amplitude of the M1. Moreover, the peak decrease in MEP amplitude after iTBS600 was significantly negatively correlated with the peak increase in MEP amplitude after cTBS600. There are no significant effects in the control group with the sham stimulation.



Motor Cortex, Transcranial Magnetic Stimulation