Data for: Change in the pattern of posttransplantation anemia in kidney receptors. Gender role in recipients and type of donor

Published: 13 May 2020| Version 2 | DOI: 10.17632/f7zrbgj992.2
Contributors:
JUAN CARLOS H HERNANDEZ RIVERA,
Bibiana Lopez López,
Felipe Octavio Rojas-Rodríguez,
José Cruz-Santiago,
Gabriela Díaz-Rosas,
Jorge Luís Mejía-Velázquez,
Ángel Verner Venegas-Vera,
Gates B. Colbert,
Carmen Velázquez-Zambrano,
Ramon Paniagua,
Jesús Eduardo Aguilera-Vallejo,
Germán Bernáldez-Gómez,
Pedro Aarón Escamilla-Galindo

Description

Introduction: Posttransplant anemia (PTA) in kidney organ receptors is a complication that has repercussions mainly of cardiovascular consequence. The objective of this study is to determine the prevalence of anemia, as well as the relationship between gender in the kidney recipient and the kidney donor, in the presence or absence of anemia at 12 months’ post kidney transplant (KT). Material and methods: Observational, longitudinal study of KT made over a 5-year period, from 2013 to 2017 in renal transplant unit from "La Raza" National Healthcare Medical Center. Three hundred twenty-eight records were analyzed. Hemoglobin (Hb) and the presence or absence of anemia according to the definition of the World Health Organization were analyzed; the association was determined between the gender of the kidney recipient and donor type (Living or deceased). For the analysis central tendency and dispersion were made, the mean difference was established with chi squared test or student’s t-test. For bivariate risk analysis was performed with significant p<0.05. Results: The mean Hb before KT was 10.38 g / dL (SD ± 2.16); Hb at 12 months was 14.47 g / dL (SD ± 2.37) 4.09 absolute increase g / dL. Kidney organ male recipients a mean of 10.54 g Hb / dL (SD ± 2.17) at 12 months 15.33 g / dL (SD ± 2.25), Δ 4.79 g / dL; female recipients Hb 10.16 g / dL (SD ± 2.13) to 13.31 g / dL (2.01 ± DE), 3.15 g of Δ g/ dL Hb, the difference between genders was 1.64 g / dL at the end of 12 months. Patients with serum creatinine (Cr) <1.2 mg / dl and anemia were 16/152 (10.5%); patients with Cr≥1.2 mg / dL and anemia were 36/176 (20.5%), p 0.014. In the bivariate logistic regression with an OR of 2.047 (95% CI 1027-4078, p=0.042) for higher Cr levels and the presence of persistent anemia. Conclusions: There is a prevalence of anemia in female kidney organ recipients and kidney organ recipients from deceased donors. There is a higher risk of persistent anemia in the case of patients with some degree of graft failure at 12 months. Keywords: posttransplantation anemia, hemoglobin pattern post-transplant, gender, anemia pattern between type of donor in kidney transplantation

Files