Supplementary data for paper "A Tiered Testing Strategy Based on In Vitro Phenotypic and Transcriptomic Data for Selecting Representative Petroleum UVCBs for Toxicity Evaluation In Vivo"
Description
• Supplementary File 1. BMDExpress output of A375 cell line, provided seperately as SuppFile1_BMD_A375.txt. The BMD values were calculated based on concentrations at 0 (vehicle controls), 1 (0.1% original extract), 10 (1 % original extract), and 100 (10 % original extract). • Supplementary File 2. BMDExpress output of induced pluripotent stem cell-derived cardiomyocytes, provided seperately as SuppFile2_BMD_iPSCCM.txt. The BMD values were calculated based on concentrations at 0 (vehicle controls), 1 (0.1% original extract), 10 (1 % original extract), and 100 (10 % original extract). • Supplementary File 3. BMDExpress output of induced pluripotent stem cell-derived endothelial cells, provided seperately as SuppFile3_BMD_ iPSCEndo.txt. The BMD values were calculated based on concentrations at 0 (vehicle controls), 1 (0.1% original extract), 10 (1 % original extract), and 100 (10 % original extract). • Supplementary File 4. BMDExpress output of induced pluripotent stem cell-derived hepatocytes, provided seperately as SuppFile4_BMD_ iPSCHep.txt. The BMD values were calculated based on concentrations at 0 (vehicle controls), 1 (0.1% original extract), 10 (1 % original extract), and 100 (10 % original extract). • Supplementary File 5. BMDExpress output of induced pluripotent stem cell-derived neurons, provided seperately as SuppFile5_BMD_ iPSCNeu.txt. The BMD values were calculated based on concentrations at 0 (vehicle controls), 1 (0.1% original extract), 10 (1 % original extract), and 100 (10 % original extract). • Supplementary File 6. BMDExpress output of MCF 7 cell line, provided seperately as SuppFile6_BMD_MCF7.txt. The BMD values were calculated based on concentrations at 0 (vehicle controls), 1 (0.1% original extract), 10 (1 % original extract), and 100 (10 % original extract). • Supplementary File 7. BMDExpress output of A375 cell line, provided seperately as SuppFile7_BMD_A375.bm2. • Supplementary File 8. BMDExpress output of induced pluripotent stem cell-derived cardiomyocytes, provided seperately as SuppFile8_BMD_iPSCCM. bm2. • Supplementary File 9. BMDExpress output of induced pluripotent stem cell-derived endothelial cells, provided seperately as SuppFile9_BMD_ iPSCEndo. bm2. • Supplementary File 10. BMDExpress output of induced pluripotent stem cell-derived hepatocytes, provided seperately as SuppFile10_BMD_ iPSCHep. bm2. • Supplementary File 11. BMDExpress output of induced pluripotent stem cell-derived neurons, provided seperately as SuppFile11_BMD_ iPSCNeu. bm2. • Supplementary File 12. BMDExpress output of MCF 7 cell line, provided seperately as SuppFile12_BMD_MCF7. bm2.