Single cell sequencing data of diabetic and traumatic tibial nerves.

Published: 8 April 2024| Version 1 | DOI: 10.17632/fpwhfxvygf.1
Xiangyun Yao


This study enrolled 24 subjects at the Department of Orthopedic Surgery of Shanghai Sixth People’s Hospital, Shanghai, China. Tibial nerves were collected during amputation surgeries in patients suffering from diabetic peripheral neuropathy (DPN) or patients with traumatic limb amputation (TLA). Nerve samples isolated from TLA patients were set as control group. For single-cell RNA sequencing experiments, tibial nerves from donors (4 DPN patients, 3 TLA patients) were rapidly frozen on liquid nitrogen in the operating room and stored until tissue digestion. The sequencing data for 4 DPN samples were named as "DPN_Sample 1-4" and the sequencing data for 3 TLA samples were named as "TLA_Sample 1-3".



Shanghai 6th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine


Single-Cell Transcriptomics