Data for: Anti-inflammatory Potential of South African Medicinal Plants used in the Treatment of Sexually Transmitted Infections

Published: 8 July 2019| Version 1 | DOI: 10.17632/fv8bz3tg8p.1
Fatimah Lawal, Thilivhali Emmanuel Tshikalange, Lyndy McGaw, Salmon Alani Adebayo, Karl Egil Malterud, Sanah Nkadimeng, Johanna Bapela


The dataset represents biological assays, conducted to determine the inhibitory activity of extracts from 12 South African medicinal plants on selected inflammatory enzymes, as well as their ability to reduce nitric oxide production, in response to inflammatory stimulation with lipopolysaccharide (LPS) in macrophage cells. The viability of macrophage cells and confirmation of cytotoxicity status of active extracts was done on Vero cells using the MTT assay. Results of antioxidant scavenging capacity of extracts are also presented. NMR spectroscopic data are presented as mestronova files while the amount of phenolic and flavonoid contents in the extracts were determined from a calibration curve of gallic acid and quercetin as shown in the data set. All experiments were carried out according to standard protocols as described in the full article.



Nuclear Magnetic Resonance Spectroscopy, Phytochemical Analysis, Enzymatic Activity, Antioxidant Capacity, Cytotoxicity Assay