Supplemental material: Efficacy of oral furosemide test for primary aldosteronism diagnosis

Published: 30 October 2023| Version 1 | DOI: 10.17632/fw8bx72v3h.1
madson almeida


Figure S1. . Flow-chart for diagnostic investigation and follow-up of patients with primary aldosteronism (PA): 64 out of 95 consecutive patients with PA met the inclusion criteria and were enrolled in this study. Figure S2. Flow-chart for recruiting patients with primary hypertension (HTN) in the Cardiology, Nephrology and Obesity clinics from our Institution. Figure S3. Direct renin concentration measures (basal, 2h and 3h after oral 80 mg furosemide) of 6 patients with low-renin hypertension, which was defined by the presence of suppressed renin levels (<4 µU/mL ) with low aldosterone concentrations (<7 ng/dL). Figure S4. . Changes in systolic blood pressure (A), diastolic blood pressure (B) and heart rate (C) at 3h in comparison to basal conditions of the oral furosemide test in patients with primary aldosteronism (PA) and hypertensive controls.



Universidade de Sao Paulo Hospital das Clinicas


Diagnosis, Diuretics, Hyperaldosteronism


Fundação de Amparo à Pesquisa do Estado de São Paulo