The influence of different regression techniques on the results obtained with SABRE, a new quantitative receptor function model; Brezniczky et al

Published: 24 February 2026| Version 1 | DOI: 10.17632/fy8gvt57zp.1
Contributor:
Rudolf Gesztelyi

Description

Furchgott-type data, obtained from rat and guinea pig atria by determining the negative inotropic response to CPA, an A1 adenosine receptor full agonist, evaluated by the SABRE and operational models. The irreversible A1 adenosine receptor antagonist was FSCPX. Data are in GraphPad Prism file.

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Steps to reproduce

Concentration-effect curves generated on paced left atrial appendages isolated from rats and guinea pigs

Institutions

Categories

Pharmacodynamics, Adenosine, Myocardial Contraction

Funders

  • the European Union and the State of Hungary
    Grant ID: TKP2021-EGA-19

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