Prothrombotic Hemostasis Disturbances in Patients with Severe COVID-19

Published: 15 October 2020| Version 1 | DOI: 10.17632/g7x5nvj9d2.1
Michael Hardy,


The aim of this prospective observational study was to describe the longitudinal changes in hemostasis parameters assessed daily in 21 COVID-19 patients during their intensive care unit (ICU) stay. Our main findings were that (i) daily standard measurements consistent with a prothrombotic state persisted over the first days and improved thereafter, but did not normalize in all patients; (ii) increased thrombin potential (hypercoagulability) and decreased fibrinolysis were frequent and (iii) a high inter-patient variability was observed.


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See: M. Hardy, I. Michaux, S. Lessire, J. Douxfils, J.-M. Dogné, M. Bareille, G. Horlait, P. Bulpa, C. Chapelle, S. Laporte, S. Testa, H. Jacqmin, T. Lecompte, A. Dive and F. Mullier. Prothrombotic Hemostasis Disturbances in Patients with Severe COVID-19: Individual daily data. Data in brief. Submitted.


CHU UCL Namur, Universite catholique de Louvain


Hematology, Intensive Care, Fibrinolysis, Blood Coagulation, COVID-19