Overlapping and touching G banded chromosome dataset

Published: 29 March 2023| Version 2 | DOI: 10.17632/h5b3zbtw8v.2


The automated Karyotyping System (AKS) is a computerized tool in the field of cytogenetics. G banded metaphase images are often the inputs to such systems. These input images usually contain overlapping and touching chromosomes. The overlapping and touching chromosome segmentation is of great research interest in the area of AKS research and development. However, the publicly available dataset in this domain is quite less. This issue is addressed with this contribution. The dataset contains 500 overlapping and touching chromosomes from G-banded metaphase images and the respective mask (label images). These G-banded metaphase images are prepared from the volunteer blood samples at the Regional Cancer Center, Thiruvananthapuram, Kerala, India, through a series of cytogenetic lab procedures. This dataset contains overlapping and touching with only two chromosomes and the respective label images. The label images are the target segmentation maps. The segmentation map provides information about the chromsome1, chromosome2, and the overlapping region between the chromosomes. This dataset can be utilized to design overlapping and touching chromosome segmentation algorithms. Version 1 of this dataset includes only the. npz file. The dataset is provided as an image dataset along with.h5 file, which are commonly used in machine learning. Version 1 describes the steps for creating image files. The steps for preparing.h5 files are provided here. 


Steps to reproduce

See version 1 and README of version 2


Regional Cancer Centre Thiruvananthapuram, College of Engineering Karunagappally


Computer Science Applications, Cytogenetics, Karyotype, Computer Engineering, Automated Segmentation, Chromosome Analysis


Kerala State Council for Science, Technology and Environment